Dusky groupers ( Epinephelus marginatus ) are characterized by a complex sex allocation strategies and overexploitation of bigger individuals. We developed an individual based model to investigate the long-term effects of density dependence on grouper population dynamics and to analyze the variabilities of extinction probabilities as a result of interacting mortalities at different life stages. We conduct several simulations with different forms of sex allocation functions and different combinations of mortality rates. The model was parametrized using data on dusky grouper (...) populations from the literature. The most important insights produced by this simulation study are that density dependence of sex allocation is an evolutionarily stable strategy, increases the population biomass, mitigates the effect of the removal of large male and indicates a need for protection of females and flexible stages. (shrink)

Proceeding of the Third International Conference of the French-Speaking Society for Theoretical Biology Content Type Journal Article Category Editorial Pages 1-2 DOI 10.1007/s10441-012-9156-2 Authors Slimane Ben Miled, ENIT-LAMSIN, Tunis el Manar University, 13, place Pasteur, Belvédère, B.P. 74, 1002 Tunis, Tunisia Journal Acta Biotheoretica Online ISSN 1572-8358 Print ISSN 0001-5342.

Dusky groupers (Epinephelus marginatus) are characterized by a complex sex allocation strategies and overexploitation of bigger individuals. We developed an individual based model to investigate the long-term effects of density dependence on grouper population dynamics and to analyze the variabilities of extinction probabilities as a result of interacting mortalities at different life stages. We conduct several simulations with different forms of sex allocation functions and different combinations of mortality rates. The model was parametrized using data on dusky grouper populations from (...) the literature. The most important insights produced by this simulation study are that density dependence of sex allocation is an evolutionarily stable strategy, increases the population biomass, mitigates the effect of the removal of large male and indicates a need for protection of females and flexible stages. (shrink)

This work presents a stock/effort model describing both harvested fish population and fishing effort dynamics. The fishing effort dynamic is controlled by investment which corresponds to the revenue proportion generated by the activity. The dynamics are subject to a set of economic and biological state constraints. The analytical study focuses on the compatibility between state constraints and controlled dynamics. By using the mathematical concept of viability kernel, we reveal situations and management options that guarantee a sustainable system.

Recently, management literature has sought to examine the role of institutional entrepreneurs in the emergence of commons logic and in building consensus around its meaning. While the focus has been on new commons, not all are created ex nihilo. Some types of preexisting commons, known as contested commons, often pose challenges that result in disagreements and conflicts with respect to their ownership, use, and management. These commons are a ubiquitous yet understudied phenomenon. In this paper, we use the case of (...) the Tunisian Oasis of Jemna, pictured against the historical backdrop of the Arab Spring, to look at the institutional struggles that involve institutional entrepreneurs and the opponents of a contested commons. We identify two main strategies used by institutional entrepreneurs to frame the commons as a superior alternative: idealizing the commons and coalescing the community to harness its potential. We also highlight the heretofore neglected role of opponents, who engage in demonizing the commons to restore the competing logics of state or market. Finally, we unravel some of the conditions that allow for a temporary settlement of the contest, leading to what we term de facto commons. (shrink)

This paper presents the first edition, translation and analyse of al-Mns commentary of the Book X of Euclid one. For the first time, irrational numbers are defined and classified. The algebraisation of Elementsrizms Algebra, shows irrational numbers as solution to algebraic quadratic equations. The algebraic calculus makes here the first steps. On this occasion, negative numbers and their calculation rules appears. Simplifications imposed by the algebraic writings are sometimes in opposition with the conclusions of propositions conceived in a purely geometrical (...) framework, revealing a contradiction between geometrical and algebraic goals. It will be resolved by the independant way algebra will take with mathematicians belonging to the tradition of al-Karajal from the 11th-12th centuries on. (shrink)

In order to find positive solutions for third-degree equations, which he did not know how to solve for roots, m proceeds by the intersections of conic sections. The representation of an algebraic equation by a geometrical curve is made possible by the choices of units of measure for lengths, surfaces, and volumes. These units allow a numerical quantity to be associated with a geometrical magnitude. Is there a trace of this unit in the mathematicians to whom al-Khayyām refers directly in (...) his Algebra? How does this unit enable the measurement of quantities and rational and irrational relations? We find answers to these questions in the commentaries to Books V and X of the Elements. (shrink)

Abstract This work is about the viability domain corresponding to a model of fisheries management. The dynamic is subject of two constraints. The biological constraint ensures the stock perennity where as the economic one ensures a minimum income for the fleets. Using the mathematical concept of viability kernel, we find out a viability domain which simultaneously enables the fleets to exploit the resource, to ensure a minimum income and stock perennity. Content Type Journal Article Category Regular Article Pages 1-19 DOI (...) 10.1007/s10441-012-9153-5 Authors C. Sanogo, LIRNE, Mathmatics Engineering Team, Ibn Tofail University, Kenitra, Morocco S. Ben Miled, ENIT-LAMSIN, Tunis el Manar University, Tunis, Tunisia N. Raissi, LAA, Mohamed V University, Rabat, Morocco Journal Acta Biotheoretica Online ISSN 1572-8358 Print ISSN 0001-5342. (shrink)

We study the viability domains of bio-economic constraints for fishing model of hermaphrodite population, displaying three stages, juvenile, female and male. The dynamic of this model is subject to two constraints: an ecological constraint ensuring the stock perennity, and an economic constraint ensuring a minimum revenue for fishermen. Using viability kernel, we find out a viability domain which simultaneously guarantees a minimum stock level and a minimum income for fleets.

pereḳ 1. ʻOśeh fele -- pereḳ 2. Ḥidud be-divre Torah -- pereḳ 3. Ḥidud be-mile de-ʻalma -- pereḳ 4. Ḳetsat shut śikhliyot ṿe-ʻimahem shene derushim le-midrash Talmud Torah.

At the beginning of a new reign it seems appropriate to re-assess the meaning of monarchy in modern Britain. The new King heads a fractured royal family, a divided nation, and a disaffected Commonwealth. How can we as scholars make sense of where the monarchy has been, and where it might be going? This article suggests a new scholarly approach is required. Through a critical analysis of three classic studies of monarchy: Walter Bagehot’s The English constitution (1867), Kingsley Martin’s The (...) magic of monarchy (1937) and Tom Nairn’s The enchanted glass (1988), the lecture traces the lineage of modern interpretations of the British monarchy and points up their limitations. Preoccupied with the symbolism of monarchy, conventional scholarship neglects its important political functions. As the lecture argues, in the era of Brexit at home and populist regimes around the world, modern democracies may actually need monarchy more than ever before. (shrink)

We propose in this article an indexing and retrieval approach applied on outline shapes. Models of objects are stored in a database using the textual descriptors of their silhouettes. We extract from the textual description a set of efficient similarity measures to index the silhouettes. The extracted features are the geometric quasi-invariants that vary slightly with the small change in the viewpoint. We use a textual description and quasi-invariant features to minimize the storage space and to achieve an efficient indexing (...) process. We also use the quad-tree structure to improve processing time during indexing. Using both geometric features and quad-tree decomposition facilitates recognition and retrieval processes. Our approach is applied on the outline shapes of three-dimensional objects. Experiments conducted on two well-known databases show the efficiency of our method in real-world applications, especially for image indexing and retrieval. (shrink)

Conditionalists say that the value something has as an end—its final value—may be conditional on its extrinsic features. They support this claim by appealing to examples: Kagan points to Abraham Lincoln’s pen, Rabinowicz and Rønnow-Rasmussen to Lady Diana’s dress, and Korsgaard to a mink coat. They contend that these things may have final value in virtue of their historical or societal roles. These three examples have become familiar: many now merely mention them to establish the conditionalist position. But the widespread (...) faith in such cases is, I believe, unjustified. This is because, surprisingly, the pen, the dress, and the coat cannot have final value. I argue that the problem is internal: these cases are ruled out by every conditionalist account of final value. Further, the problem with these well-known cases applies to most other supposed examples of extrinsic, final goods. Thus nearly all cases given to support the conditionalist view cannot succeed. I suggest a kind of diagnosis: I claim that these examples are best seen as instances of sentimental value, rather than final value. I close by providing a brief account of sentimental value and explain how it relates to instrumental, intrinsic, and final goodness. (shrink)

After briefly outlining the fine-tuning argument (FTA), I explain how it relies crucially on the claim that it is not improbable that God would design a fine-tuned universe. Against this premise stands the divine psychology objection: the contention that the probability that God would design a fine-tuned universe is inscrutable. I explore three strategies for meeting this objection: (i) denying that the FTA requires any claims about divine psychology in the first place, (ii) defining the motivation and intention to design (...) a fine-tuned universe into the theistic hypothesis, and (iii) providing arguments that the relevant probability is not terribly low. While I reject the first two, I conclude, in line with the third, that considerations about life's objective value establish that it is not absurdly improbable that God would design a fine-tuned universe, whether one regards the FTA as an inference merely to a cosmic designer, or to theism proper. Accordingly, the divine psychology objection fails. (shrink)

Research on interdisciplinary science has for the most part concentrated on the institutional obstacles that discourage or hamper interdisciplinary work, with the expectation that interdisciplinary interaction can be improved through institutional reform strategies such as through reform of peer review systems. However institutional obstacles are not the only ones that confront interdisciplinary work. The design of policy strategies would benefit from more detailed investigation into the particular cognitive constraints, including the methodological and conceptual barriers, which also confront attempts to work (...) across disciplinary boundaries. Lessons from cognitive science and anthropological studies of labs in sociology of science suggest that scientific practices may be very domain specific, where domain specificity is an essential aspect of science that enables researchers to solve complex problems in a cognitively manageable way. The limit or extent of domain specificity in scientific practice, and how it constrains interdisciplinary research, is not yet fully understood, which attests to an important role for philosophers of science in the study of interdisciplinary science. This paper draws upon two cases of interdisciplinary collaboration; those between ecologists and economists, and those between molecular biologists and systems biologists, to illustrate some of the cognitive barriers which have contributed to failures and difficulties of interactions between these fields. Each exemplify some aspect of domain specificity in scientific practice and show how such specificity may constrain interdisciplinary work. (shrink)

This paper defends the view, put roughly, that to think that p is to guess that p is the answer to the question at hand, and that to think that p rationally is for one’s guess to that question to be in a certain sense non-arbitrary. Some theses that will be argued for along the way include: that thinking is question-sensitive and, correspondingly, that ‘thinks’ is context-sensitive; that it can be rational to think that p while having arbitrarily low credence (...) that p; that, nonetheless, rational thinking is closed under entailment; that thinking does not supervene on credence; and that in many cases what one thinks on certain matters is, in a very literal sense, a choice. Finally, since there are strong reasons to believe that thinking just is believing, there are strong reasons to think that all this goes for belief as well. (shrink)

However, the barriers and facilitators of such changes - law reform perspectives - have been virtually ignored. Why do so many attempts to change the law fail but others are successful? International Perspectives on End-of-Life Law Reform aims to address this question by drawing on ten case studies of end-of-life law reform from the United Kingdom, the United States, Canada, the Netherlands, Belgium and Australia. Written by leading end-of-life scholars, the book's chapters blend perspectives from law, medicine, bioethics and sociology (...) to examine sustained reform efforts to permit assisted dying and change the law about withholding and withdrawing life-sustaining treatment. Findings from this book not only shed light on changing end-of-life law but also provide insight more generally into how and why law reform succeeds in complex and controversial social policy areas. (shrink)

Narrative analysis is well established as a means of examining the subjective experience of those who suffer chronic illness and cancer. In a study of perceptions of the outcomes of treatment of cancer of the colon, we have been struck by the consistency with which patients record three particular observations of their subjective experience: the immediate impact of the cancer diagnosis and a persisting identification as a cancer patient, regardless of the time since treatment and of the presence or absence (...) of persistent or recurrent disease; a state of variable alienation from social familiars, expressed as an inability to communicate the nature of the experience of the illness, its diagnosis and treatment; and a persistent sense of boundedness, an awareness of limits to space, empowerment and available time. These subjectivities were experienced in varying degree by all patients in our study. Individual responses to these experiences were complex and variable. The experiences are best understood under the rubric of a category we call “liminality”. We believe that all cancer patients enter and experience liminality as a process which begins with the first manifestations of their malignancy. An initial acute phase of liminality is marked by disorientation, a sense of loss and of loss of control, and a sense of uncertainty. An adaptive, enduring phase of suspended liminality supervenes, in which each patient constructs and reconstructs meaning for their experience by means of narrative. This phase persists, probably for the rest of the cancer patient’s life. The experience of liminality is firmly grounded in the changing and experiencing body that houses both the disease and the self. Insights into the nature of the experience can be gained from the Existentialist philosophers and from the history of attitudes to death. Understanding liminality helps us to understand what it is that patients with cancer seek from the system to which they turn for help. Its explication should therefore be important for those who provide health care, those who educate health care workers and those concerned to study and use outcomes as administrative and policy making instruments. (shrink)

I consider Agnes Callard's _Aspiration_, primarily with regard to its characterization of aspirants as having a partial grasp of a value and being oriented toward their own self-improvement, and to its descriptions of individual case studies, primarily those of Alcibiades and the "good music student" who wishes to learn more about music for its own sake. While she surely has a real phenomenon in view, her theorization of it is more baffling than enlightening, hemmed in by bizarre side conditions on (...) what could count as a reason for pursuing something and by curiously anhedonic exemplars. Her agents have no actual desire to engage in their pursuits, only intellectual respect for them, and no reason to do so: Callard substitutes for "partial grasp of a reason" the idea of two-faced "proleptic reason", whose two faces are a non-aspirational reason the agent has and an aspirational reason the agent doesn't have. Despite the book's subtitle and occasional obiter dicta, she has no concept of becoming, or agents who understand themselves as deepening their engagement with something out of interest in it. (shrink)

In this paper we take a close look at current interdisciplinary modeling practices in the environmental sciences, and suggest that closer attention needs to be paid to the nature of scientific practices when investigating and planning interdisciplinarity. While interdisciplinarity is often portrayed as a medium of novel and transformative methodological work, current modeling strategies in the environmental sciences are conservative, avoiding methodological conflict, while confining interdisciplinary interactions to a relatively small set of pre-existing modeling frameworks and strategies (a process we (...) call crystallization). We argue that such practices can be rationalized as responses in part to cognitive constraints which restrict interdisciplinary work. We identify four salient integrative modeling strategies in environmental sciences, and argue that this crystallization, while contradicting somewhat the novel goals many have for interdisciplinarity, makes sense when considered in the light of common disciplinary practices and cognitive constraints. These results provide cause to rethink in more concrete methodological terms what interdisciplinarity amounts to, and what kinds of interdisciplinarity are obtainable in the environmental sciences and elsewhere. (shrink)

I present and evaluate three interpretations of methodological naturalism (MN), the principle that scientific explanations may only appeal to natural phenomena: as an essential feature of science, as a provisional guideline grounded in the historical failure of supernatural hypotheses, and as a synthesis of these two approaches. In doing so, I provide both a synoptic overview of current scholarship on MN, as well a contribution to that discussion by arguing in favor of a restricted version of MN, placing it on (...) a firmer theoretical foundation than that supplied by previous studies, and replying to recent objections. (shrink)

Well-Being and Death addresses philosophical questions about death and the good life: what makes a life go well? Is death bad for the one who dies? How is this possible if we go out of existence when we die? Is it worse to die as an infant or as a young adult? Is it bad for animals and fetuses to die? Can the dead be harmed? Is there any way to make death less bad for us? Ben Bradley defends the (...) following views: pleasure, rather than achievement or the satisfaction of desire, is what makes life go well; death is generally bad for its victim, in virtue of depriving the victim of more of a good life; death is bad for its victim at times after death, in particular at all those times at which the victim would have been living well; death is worse the earlier it occurs, and hence it is worse to die as an infant than as an adult; death is usually bad for animals and fetuses, in just the same way it is bad for adult humans; things that happen after someone has died cannot harm that person; the only sensible way to make death less bad is to live so long that no more good life is possible. (shrink)

Integrative systems biology is an emerging field that attempts to integrate computation, applied mathematics, engineering concepts and methods, and biological experimentation in order to model large-scale complex biochemical networks. The field is thus an important contemporary instance of an interdisciplinary approach to solving complex problems. Interdisciplinary science is a recent topic in the philosophy of science. Determining what is philosophically important and distinct about interdisciplinary practices requires detailed accounts of problem-solving practices that attempt to understand how specific practices address the (...) challenges and constraints of interdisciplinary research in different contexts. In this paper we draw from our 5-year empirical ethnographic study of two systems biology labs and their collaborations with experimental biologists to analyze a significant problem-solving approach in ISB, which we call adaptive problem solving. ISB lacks much of the methodological and theoretical resources usually found in disciplines in the natural sciences, such as methodological frameworks that prescribe reliable model-building processes. Researchers in our labs compensate for the lack of these and for the complexity of their problems by using a range of heuristics and experimenting with multiple methods and concepts from the background fields available to them. Using these resources researchers search out good techniques and practices for transforming intractable problems into potentially solvable ones. The relative freedom lab directors grant their researchers to explore methodological options and find good practices that suit their problems is not only a response to the complex interdisciplinary nature of the specific problem, but also provides the field itself with an opportunity to discover more general methodological approaches and develop theories of biological systems. Such developments in turn can help to establish the field as an identifiably distinct and successful approach to understanding biological systems. (shrink)

In this article, we provide a case study examining how integrative systems biologists build simulation models in the absence of a theoretical base. Lacking theoretical starting points, integrative systems biology researchers rely cognitively on the model-building process to disentangle and understand complex biochemical systems. They build simulations from the ground up in a nest-like fashion, by pulling together information and techniques from a variety of possible sources and experimenting with different structures in order to discover a stable, robust result. Finally, (...) we analyze the alternative role and meaning theory has in systems biology expressed as canonical template theories like Biochemical Systems Theory. (shrink)

I argue that there are two distinct views called ‘value pluralism’ in contemporary axiology, but that these positions have not been properly distinguished. The first kind of pluralism, weak pluralism, is the view philosophers have in mind when they say that there are many things that are valuable. It is also the kind of pluralism that philosophers like Moore, Brentano and Chisholm were interested in. The second kind of pluralism, strong pluralism, is the view philosophers have in mind when they (...) say there are many values, or many kinds of value. It is also the kind of pluralism that philosophers like Stocker, Kekes and Nussbaum have advanced. I separate and elucidate these views, and show how the distinction between them affects the contemporary debate about value pluralism. (shrink)

The importation of computational methods into biology is generating novel methodological strategies for managing complexity which philosophers are only just starting to explore and elaborate. This paper aims to enrich our understanding of methodology in integrative systems biology, which is developing novel epistemic and cognitive strategies for managing complex problem-solving tasks. We illustrate this through developing a case study of a bimodal researcher from our ethnographic investigation of two systems biology research labs. The researcher constructed models of metabolic and cell-signaling (...) pathways by conducting her own wet-lab experimentation while building simulation models. We show how this coupling of experiment and simulation enabled her to build and validate her models and also triangulate and localize errors and uncertainties in them. This method can be contrasted with the unimodal modeling strategy in systems biology which relies more on mathematical or algorithmic methods to reduce complexity. We discuss the relative affordances and limitations of these strategies, which represent distinct opinions in the field about how to handle the investigation of complex biological systems. (shrink)

Computational intelligence techniques are being investigated as an extension of the traditional fault diagnosis methods. This article presents, for the first time, a scheme for fault detection and isolation via artificial neural networks and fuzzy logic. It deals with the sensor fault of a three-link selective compliance assembly robot arm robot. A second scheme is proposed for fault detection and accommodation via analytical redundancy, and it deals with the sensor fault of a three-link SCARA robot. These proposed FDI approaches are (...) implemented on Matlab/simulink software and tested under several types of faults. The results show the importance of this process. Then, the sensor faults are detected and isolated successfully. Also, the actuator faults are detected and a fault tolerance strategy is used for reconfigurable control using a sliding-mode observer. (shrink)

The study investigated the extent to which defensive functioning and defense mechanisms predict clinically meaningful symptomatic improvement within brief psychodynamic psychotherapy for recurrent and chronic depression in an inpatient setting. Treatment response was defined as a reduction in symptom severity of 46% or higher from the baseline score on the Montgomery–Asberg Depression Rating Scale. A subsample of 41 patients from an RCT was included. For each case, two sessions of brief inpatient psychodynamic psychotherapy were transcribed and then coded using the (...) Defense Mechanism Rating Scales and the Psychotic Defense Mechanism Rating Scales, an additional scale developed to study psychotic defenses. Results showed that defensive functioning and mature and immature defense changed during psychotherapy and predicted treatment response. Patient’s defenses observed throughout therapy also predicted treatment response at 12-month follow-up. The addition of psychotic defenses allows a better prediction of the treatment response. Overall, these results are in line with previous research and provide further validation of defensive functioning as a predictor of outcomes and a mechanism of change in psychotherapy. (shrink)

Explores the importance of political judgment in the work of Bernard Stiegler, and argues his approach to judgment marks an important break with continental political thought.

Mooreans claim that intrinsic goodness is a conceptual primitive. Fitting-attitude theorists object: they say that goodness should be defined in terms of what it is fitting for us to value. The Moorean view is often considered a relic; the fitting-attitude view is increasingly popular. I think this unfortunate. Though the fitting-attitude analysis is powerful, the Moorean view is still attractive. I dedicate myself to the influential arguments marshaled against Moore’s program, including those advanced by Scanlon, Stratton-Lake and Hooker, and Jacobson; (...) I argue that they do not succeed. (shrink)

While Spinoza is often interpreted as an early secular or liberal thinker, this book argues that such interpretations neglect the senses of order and authority that are at the heart of Spinoza’s idea of God. For Spinoza, God is an organized and directed totality of all that exists. God is entirely immanent to this totality, to such an extent that all things are fundamentally of God. Appreciating the full extent to which God permeates and orders every aspect of reality, allows (...) the full sense of Spinoza’s theories of tolerance and the social contract to come into view. Rather than assuming that human beings involved in political relationships are independent, autonomous individuals, for Spinoza they are parts of a larger whole subject to distinct natural laws. Spinoza maintains that such laws manifest themselves equally and identically in the seemingly distinct realms of religion and politics. In this respect, Spinoza’s theories of religion and biblical interpretation are not properly secular in character but rather blur the standard boundary between the religious and the political as they try to recognize and codify the inviolable laws of nature - or God. (shrink)

The results of two experiments are analyzed to find out how artistic expertise influences visual search. Experiment I comprised survey data of 1,065 students on self-reported visual memory skills and their ability to find three targets in four images of artwork. Experiment II comprised eye movement data of 50 Visual Literacy experts and non-experts whose eye movements during visual search were analyzed for nine images of artwork as an external validation of the assessment tasks performed in Sample I. No time (...) constraint was set for completion of the visual search task. A latent profile analysis revealed four typical solution patterns for the students in Sample I, including a mainstream group, a group that completes easy images fast and difficult images slowly, a fast and erroneous group, and a slow working student group, depending on task completion time and on the probability of finding all three targets. Eidetic memory, performance in art education and visual imagination as self-reported visual skills have significant impact on latent class membership probability. We present a hidden Markov model approach to uncover underlying regions of attraction that result from visual search eye-movement behavior in Experiment II. VL experts and non-experts did not significantly differ in task time and number of targets found but they did differ in their visual search process: compared to non-experts, experts showed greater precision in fixating specific prime and target regions, assessed through hidden state fixation overlap. Exploratory analysis of HMMs revealed differences between experts and non-experts in image locations of attraction. Experts seem to focus their attention on smaller image parts whereas non-experts used wider parts of the image during their search. Differences between experts and non-experts depend on the relative saliency of targets embedded in images. HMMs can determine the effect of expertise on exploratory eye movements executed during visual search tasks. Further research on HMMs and art expertise is required to confirm exploratory results. (shrink)

High-dose chemotherapy and autologous stem cell transplantation is used to treat some advanced malignancies. It is a traumatic procedure, with a high complication rate and significant mortality. ASCT patients and their carers draw on many sources of information as they seek to understand the procedure and its consequences. Some seek information from beyond orthodox medicine. Alternative beliefs and practices may conflict with conventional understanding of the theory and practice of ASCT, and ‘contested understandings’ might interfere with patient adherence to the (...) strict and demanding protocols required for successful ASCT.The present study, conducted in Sydney, Australia, examines narrative-style interviews with 10 sequentially recruited ASCT patients and nine of their carers conducted at the time of transplant and three months later. Transcripts were read for instances of mention of alternative advice, and for instances of contested understanding of information relevant to the transplant.Patients and carer pairs expressed closely concordant views about alternative advice. Five pairs were consulting alternative practitioners. Contested understanding was expressed in four domains—understandings of the transplant itself and its underlying theory, of the relationship between the components of the ‘transplant’, of the nature and role of stem cells, and of beliefs about bodily function and life-style. Contested understandings of the transplant treatment were expressed as predominantly personal interpretations of orthodox informationPatients and carers seemed to recognise that alternative and conventional systems were discordant, yet they were able to separate the two, and adhere to each practice without prejudicing their medical treatment. A single case of late, post-transplant repudiation of Western medicine is discussed to emphasise some of the possible determinants of dissonance when it does occur. (shrink)